PDRN Injections in Seoul, Korea
PDRN injections use DNA-derived polydeoxyribonucleotide to repair and regenerate skin, boosting collagen, hydration and barrier strength for smoother, healthier skin, at NEST Clinic, Gangnam.
- Session 10–20 min
- Downtime About 1 day
- Glow 3–5 days
- Lasts 2–4 months
🌸 Quick answer
What are PDRN injections? PDRN injections deliver polydeoxyribonucleotide, a skin-regenerating ingredient derived from DNA fragments, into the dermis. PDRN stimulates cell repair, boosts collagen, improves hydration and strengthens the skin barrier, so it is often called a healing injection. It is gentle and suits even sensitive skin. Early glow usually appears within three to five days, with fuller regeneration over three to four weeks, and results typically last two to four months.
What are PDRN injections?
PDRN (polydeoxyribonucleotide) is a regenerating molecule derived from purified DNA fragments. Injected into the dermis, it helps repair damaged tissue, supports collagen and strengthens the skin barrier. It is a gentle, restorative skin booster often chosen as a natural alternative to fillers and lasers.
It is also used to calm and repair skin after procedures such as lasers or microneedling, and it pairs well with other boosters in a radiance routine.
What it improves
- Dull, dehydrated or fatigued skin
- Uneven texture and early fine lines
- Redness and inflammation
- Under-eye tiredness and mild dark circles
- A weakened or thin skin barrier
Why people choose it
- Gentle and suitable for sensitive skin
- Strengthens and repairs the barrier
- Calms skin after lasers or microneedling
- Natural rejuvenation without added volume
Before & after: what changes
The skin looks calmer, smoother and more radiant as it repairs over the first weeks.
Who are PDRN injections for?
A good fit if you
- Want brighter, smoother skin without volume
- Have sensitive or easily irritated skin
- Need calming and repair after a laser
- Prefer natural, regenerative rejuvenation
Less suitable if you
- Want structural volume (consider facial fillers)
- Have an active skin infection in the area
- Are pregnant or breastfeeding without doctor advice
How a PDRN session works
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Skin assessment
The doctor maps the target areas such as the face or under-eyes.
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Micro-injection
Fine micro-injections place PDRN evenly across the treatment area.
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Repair phase
PDRN works gradually to repair skin cells; mild redness or tiny marks may appear briefly. Session time: 10–20 minutes.
Recovery and results timeline
Downtime is minimal. Mild redness or pinpoint marks may last about a day, and skin often looks calmer within the first week.
- Day 0 Back to normal activities
- 3–5 days Early glow appears
- 1–2 weeks Noticeably smoother skin
- 3–4 weeks Fuller regeneration effect
PDRN injections at a glance
Cost depends on the number of sessions and area. International patients pay the same local price, confirmed at consultation.
| Active ingredient | Polydeoxyribonucleotide (PDRN) |
|---|---|
| Session time | 10–20 minutes |
| Anaesthesia | Numbing cream on request |
| Downtime | About 1 day |
| Results start | Glow in 3–5 days |
| Duration | 2–4 months; often repeated in a course |
| Cost | Confirmed at consultation; international patients pay the same local price |
Aftercare tips
- Avoid heat, sweating and exercise for 24 hours
- Do not exfoliate for several days
- Keep skin moisturised with gentle products
- Use sunscreen daily to protect repairing skin
Medically reviewed by
Dr. Sohee Joo · Chief Executive Doctor, NEST Clinic
Medytox Best Doctor · Restylane (Galderma) Medical Advisor · Key Doctor for several injectable brands. M.Sc., Dongguk University College of Medicine; specialist training at Dongguk University Medical Center.
PDRN Injections FAQ
How many PDRN sessions do I need?
PDRN is often given as a short course of several sessions spaced one to two weeks apart, then maintained periodically. Your doctor will tailor the number to your skin.
Do PDRN injections hurt?
Discomfort is mild. Numbing cream can be applied, and most people feel small pinches. Brief redness or tiny marks may follow.
What is the difference between PDRN and PN injections?
Both are DNA-derived repair molecules. PDRN refers to polydeoxyribonucleotide, while PN (polynucleotide) products such as salmon-derived injections use longer chains. Effects overlap and your doctor will choose the suitable option.
Can PDRN be used after a laser?
Yes. PDRN is often used to calm and speed recovery after lasers or microneedling because it supports barrier repair and reduces redness.
How long do results last?
Results usually last two to four months depending on your skin, and a maintenance session helps sustain the improvement.
Is PDRN safe for sensitive skin?
Yes. PDRN is gentle and is often chosen specifically for sensitive, reactive or post-procedure skin. A doctor checks for active infection first.
Often considered with PDRN injections
Want calmer, healthier skin?
Tell us about your skin and any recent treatments on WhatsApp, and our doctors will plan a PDRN course that suits your barrier and concerns.