✿ Skin repair · Regenerative

Salmon Sperm Injections in Seoul, Korea

Salmon sperm injections use polynucleotides, gentle DNA-derived molecules, to regenerate and repair the skin, boosting hydration, elasticity and a healthy glow, at NEST Clinic, Gangnam.

  • Session 10–20 min
  • Downtime About 1 day
  • Glow 3–5 days
  • Lasts 3–6 months
Polynucleotide salmon-DNA skin regeneration injection at NEST Clinic, Gangnam

🌸 Quick answer

What are salmon sperm injections? Salmon sperm injections use polynucleotides, DNA-derived molecules purified from salmon, to regenerate and repair the skin. They support cell turnover, deep hydration and elasticity, making skin look brighter and healthier. Part of Korea's skin-regeneration trend, they focus on natural healing rather than adding volume. Early radiance usually appears within three to five days, with fuller effects over three to four weeks, and results typically last three to six months.

What are salmon sperm injections?

Salmon sperm injections deliver polynucleotides (PN), gentle DNA-derived molecules, into the skin to support repair and regeneration. They improve cell turnover, hydration and elasticity, which is why they suit tired, dull or damaged skin. They are a regenerative skin booster rather than a volumising filler.

Because they work by healing rather than filling, results build gradually and look natural. They are closely related to PDRN injections and Rejuran-type treatments.

What it improves

  • Dull, fatigued skin
  • Uneven texture or roughness
  • Dark circles and under-eye tiredness
  • Early fine lines and dehydration
  • A weakened skin barrier

Why people choose it

  • Deep hydration for glass-skin glow
  • Strengthens and repairs the barrier
  • Gentle, suitable for most skin types
  • Natural regeneration without volume

Before & after: what changes

The skin looks healthier, smoother and more radiant as it regenerates over the first weeks.

Illustration of skin before and after salmon sperm injections Left: dull, tired-looking skin. Right: brighter, smoother, more hydrated skin. Before After 2–4 weeks ✿ polynucleotide repair dull · tired bright · plump
Illustration for explanation only — not an actual patient photo. Individual results vary.

Who are salmon sperm injections for?

A good fit if you

  • Want smoother, healthier, brighter skin
  • Have dryness or sensitivity
  • Want a refreshed under-eye area
  • Prefer a gentle, regenerative approach

Less suitable if you

  • Want structural volume (see facial fillers)
  • Have an active skin infection in the area
  • Are pregnant or breastfeeding without doctor advice

How a salmon sperm injection session works

  1. Skin evaluation

    The doctor identifies your concerns and the areas to treat, such as the face or under-eyes.

  2. Micro-injection

    Fine micro-injections distribute the polynucleotide solution evenly in the dermis.

  3. Repair phase

    The polynucleotides work deep in the skin to repair cells; temporary redness or marks may appear. Session time: 10–20 minutes.

Recovery and results timeline

Downtime is minimal. Mild redness or pinpoint marks may appear and fade quickly, and skin often looks fresher within the first week.

  1. Day 0 Back to normal activities
  2. 3–5 days Radiance begins
  3. 1–2 weeks Texture improves
  4. 3–4 weeks Full regeneration effect

Salmon sperm injections at a glance

Cost depends on the product and number of sessions. International patients pay the same local price, confirmed at consultation.

Active ingredient Polynucleotides (salmon-derived DNA)
Session time 10–20 minutes
Anaesthesia Numbing cream on request
Downtime About 1 day
Results start Radiance in 3–5 days
Duration 3–6 months; often done in a course
Cost Confirmed at consultation; international patients pay the same local price

Aftercare tips

  • Avoid strenuous exercise and saunas for 24 hours
  • Keep skin moisturised with gentle products
  • Avoid exfoliation for a few days
  • Use sunscreen daily; mild redness fades quickly
Dr. Sohee Joo, Chief Executive Doctor at NEST Clinic

Medically reviewed by

Dr. Sohee Joo · Chief Executive Doctor, NEST Clinic

Medytox Best Doctor · Restylane (Galderma) Medical Advisor · Key Doctor for several injectable brands. M.Sc., Dongguk University College of Medicine; specialist training at Dongguk University Medical Center.

Last reviewed: October 2026 · This page is general information, not medical advice. Suitability is decided by a doctor at consultation.

Salmon Sperm Injections FAQ

Do salmon sperm injections really contain salmon DNA?

They contain polynucleotides purified from salmon DNA, not sperm cells. The name is a popular nickname; the product is a refined, sterile regenerative molecule.

How many sessions will I need?

They are usually given as a short course of several sessions spaced one to two weeks apart, then maintained periodically. Your doctor will tailor the plan to your skin.

Do the injections hurt?

Discomfort is mild. Numbing cream can be applied, and most people feel small pinches, with brief redness afterwards.

How are these different from PDRN injections?

Both are DNA-derived repair treatments. PDRN uses shorter fragments, while polynucleotide (PN) products use longer chains. Effects overlap and your doctor will choose the right one.

How long do results last?

Results usually last three to six months depending on your skin and lifestyle, and maintenance sessions help sustain the glow.

Are they safe for sensitive skin?

Yes. Polynucleotide injections are gentle and often chosen for sensitive, dry or tired skin. A doctor checks for active irritation or infection first.

Often considered with salmon sperm injections

✿ Free consultation

Want naturally healthier skin?

Tell us your main concern on WhatsApp, and our doctors will plan a polynucleotide course to repair and brighten your skin.